The ADN mission is to build capacity for the advancement of inter- and transdisciplinary research on the social-ecological impacts of hydroelectric dam construction in the Amazon. The network aims to synthesize and share lessons learned from hydroelectric dam  implementation in the Amazon and the United States focusing on an adaptive management approach within the complex social-ecological systems (SES) theory.

The geographical focus includes the Tocantins, Madeira and Xingu River watersheds in the Amazon, and the Colorado River watershed in the US, specifically focusing on the Glen Canyon Dam Adaptive Management Program (GCDAMP).

The ADN initial group of participants includes researchers from diverse fields, representatives from governmental and non-governmental institutions, and underrepresented social groups from the US, Brazil, Bolivia and Peru.

In Brazil, ADN leaders are the Amazonian Universities Federal University of Rondônia (UNIR) and Federal University of Tocantins (UFT).

In the US, the ADN is hosted in the Tropical Conservation and Development Program in the Center for Latin American Studies at the University of Florida. It also partners with the USGS Glen Canyon Dam Adaptive Management Program (GCDAMP).